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The running buffer (assay buffer) is a critical component of lateral flow assays (LFAs), as it serves to carry the sample and conjugate through the test strip. The running buffer also plays a key role in controlling flow rate and direction, which is essential for accurate and reliable results. In addition, the running buffer can impact the sensitivity, specificity, and stability of the assay. Creative Diagnostics helps customers formulate suitable running buffers by using various salts, detergents, surfactants, stabilizing agents, or blocking reagents. This allows them to buffer sample pH, minimize non-specific binding, neutralize interferents, and control flow speed.